(NYSE:UTX). With rollout to customers expected in early 2017, the new solution will help further enable rapid diagnosis and resolution of issues in http://pokentedidly61b56.journalnewsnet.com/udall-scholarship-offers-5000-scholarships-every-year-to-80-undergrads-who-are-looking-to-enter-environmental-studies-and-native-health-care-1 the field by making it possible for medical interview birmingham remote experts to inspect engines “virtually” in close collaboration with the customer. The platform provides a live and interactive link between the customer, P&WC’s field support representative and the P&WC customer engineer, which captures high quality video and images even in low-bandwidth areas where Wi-Fi and cellular signals are weak. Thanks to this dynamic connection, teams will be better equipped to rapidly troubleshoot issues and make proactive and preventive maintenance decisions – even if they are in remote locations on opposite sides of the globe. The solution, which is accessed via a software app installed on the remote expert’s computer and the customer’s smartphone, can save up to 12 hours by delivering virtual on-site support and technical expertise to the customer where and when they need it. “We continue to invest in technologies and solutions that enable proactive and predictive maintenance and data-driven decisions that positively impact our customers’ bottom line through increased aircraft availability and reduced costs,” said Timothy Swail, Vice President, Customer Programs, P&WC. “The Onsight solution keeps us connected with customers in their environments in real time and provides immediate access to remote experts for rapid problem solving and issue resolution.” In addition to live video and audio, the platform includes features such as borescope connectivity, remote-camera control (camera angle, lighting, etc.), on-screen drawing and image sharing. The Onsight solution provides the ability to develop knowledge-based content, improve maintenance team productivity, and deliver effective remote training of maintenance teams in the field. Videos can be recorded for future customer use, training and reference and the Onsight solution enhances the confidentiality of information by means of advanced wireless security, authentication and encryption, network hop over to this site controls and privacy settings. P&WC will be at NAAA 2016 at booth #739.
For the original version including any supplementary images or video, visit http://www.aviationpros.com/press_release/12284626/pratt-whitney-canada-enhances-service-capabilities-with-virtual-presence-customer-collaboration-solution
“So that was our first clue that the pericytes were possibly doing something harmful in the early stages of an ischemic stroke.” It is well known that the BBB becomes dysfunctional when genetic defects disrupt pericyte-endothelial signaling from birth. However, very little is known about how normally developed pericytes in the adult brain respond during acute ischemia, and only one or two studies have investigated this in vivo. “Pericytes have a lot of potential functions–they seem to be a sort of a jack-of-all-trades,” said Shih. “We’ve had an idea of what these cells do, but we haven’t been able to visualize and track them in vivo until recently.” The team was also intrigued by a handful of published studies showing that various inflammatory signaling cascades can induce pericyte MMP-9 expression. “The problem is that, like pericytes, MMPs are hard to study in vivo–most of what we know about them is from studies on cultured cells or extracted brains,” said Underly. “We wanted to probe this process in live animals so we could see the spatiotemporal relationship between pericytes and MMP activation in vivo–in the acute stroke time frame.” To do this, the team combined several novel tools to create a unique study protocol using transgenic mice, two-photon fluorescent microscopy, and a fluorescent gelatin-based reporter of MMPs that only one other research group had ever used to study the intact brain. The researchers also used photothrombosis to block blood flow in a small area of the capillary bed and imaged transgenic http://milamasonhome.haralsoncounty.org/2016/10/03/the-options-for-essential-aspects-for-interview-for-consultant mouse lines expressing bright fluorescent reporters specifically in the pericytes to clearly identify them. “The successful combination of technologies is certainly one of the innovations of this project,” said Shih. “It’s the first study to combine these tools to look at the relationship among pericytes, MMP activity, and BBB leakage in ischemia.” Their findings revealed that ischemia resulted in extremely rapid (within tens of minutes), localized activation of MMP-9 and plasma leakage. Furthermore, plasma leakage occurred preferentially where the pericyte somata adjoined the capillary wall–not homogeneously along the length of the capillaries as previously imagined by the group.
For the original version including any supplementary images or video, visit https://www.eurekalert.org/pub_releases/2016-12/muos-aio120216.php
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